Welcome to the Kisley Lab
Materials at the ultimate concentration limit
We are a team of physicists, chemists, and engineers driven by curiosity to understand the world at the limit of a single molecule.
We study materials using nanoscale microscopy. We have the goal to inspire materials design through the following aims:
1) Approach medical & industrial material problems with a molecular, quantitative perspective using single molecule spectroscopy. Single molecule spectroscopy accesses heterogeneity hidden in traditional ensemble measurements.
2) Advance the single molecule materials field towards more complex, realistic conditions. We have a long-term vision of connecting the molecular results to the macroscale material performance.
3) Develop new microscopies that achieve a full physicochemical picture of molecular behavior. This includes how molecules adsorb, diffuse, and fold over space, time, and temperature.
Please check out our website for more details!
Research & Discoveries
The Kisley Lab images molecules interacting with bio/soft/metal materials using microscopy.
We track how molecules stick, move, react, or change conformation over space, time, and temperature.
Protein Dynamics in the Extracellular Matrix
How do proteins behave outside the cell?
Diffusion and Adsorption of Analytes in Separation Materials
Designing the most challenging separations from the bottom-up
Imaging Corrosion, One Redox Reaction at a Time
Detecting & understanding rust right when it starts
New High-Resolution Microscopy Methods
Reaching new scales even with noisy or low signal data
Learn more about our research:
Notable News
Lydia gives keynote presentation at CWRU's first Biophysics Week event
3/20/2024
The CWRU Postdoc Association’s Professional Development Committee hosted the inaugural CWRU Biophysics Day! The purpose of the event was to celebrate biophysics, promote interdisciplinary collaboration, share research being done on campus. Lydia was invited to give the featured Research Talk and covered the lab's work on imaging the extracellular environment.
Congratulations - JES publication
4/24/2024
Congratulations to Lian, Zechariah, and Mark on their article "A turn-off fluorescent sensor for metal ions quantifies corrosion in an organic solvent" in the Journal of the Electrochemical Society. The work is in press, but you can check out the preprint here: DOI: 10.26434/chemrxiv-2023-53g68-v2
Group attends APS March Meeting
3/3- 3/8/2024
The Kisley Lab took over the APS March Meeting in Minneapolis! The group had seven talks & one poster over the course of the meeting in DBIO, DSOFT, DCP, DPOLY, DFD, and GIMS.
Contact Us
Rockefeller Bldg.
2076 Adelbert Rd.
Cleveland, OH 44106-7079
216-368-2118
