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Welcome to the Kisley Lab

Materials at the ultimate concentration limit

We are a team of physicists, chemists, and engineers driven by curiosity to understand the world at the limit of a single molecule.

We study materials using nanoscale microscopy. We have the goal to inspire materials design through the following aims:

1) Approach medical & industrial material problems with a molecular, quantitative perspective using single molecule spectroscopy. Single molecule spectroscopy accesses heterogeneity hidden in traditional ensemble measurements.

2) Advance the single molecule materials field towards more complex, realistic conditions. We have a long-term vision of connecting the molecular results to the macroscale material performance.

3) Develop new microscopies that achieve a full physicochemical picture of molecular behavior. This includes how molecules adsorb, diffuse, and fold over space, time, and temperature.

 

Please check out our website for more details!

Research & Discoveries

The Kisley Lab images molecules interacting with bio/soft/metal materials using microscopy.
We track how molecules stick, move, react, or change conformation over space, time, and temperature.

Image by Josie Weiss

Protein Dynamics in the Extracellular Matrix

How do proteins behave outside the cell?

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Diffusion and Adsorption of Analytes in Separation Materials

Designing the most challenging separations from the bottom-up

Image by Tengyart

Imaging Corrosion, One Redox Reaction at a Time

Detecting & understanding rust right when it starts

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New High-Resolution Microscopy Methods

Reaching new scales even with noisy or low signal data

Learn more about our research:

Notable News

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Lydia gives keynote presentation at HPLC 2024

7/22/2024

Lydia was invited to give a keynote research talk on the lab's research on microscopic studies of liquid chemical separations at HPLC 2024 in Denver. It was great to meet with so many separation scientists that spanned academia, government, and industry.

Congratulations - Journal of Applied Physics paper

9/4/2024

Congratulations to Stephanie, along with co-authors Mai and Cole, on their manuscript "A practical guide to light-sheet microscopy for nanoscale imaging: Looking beyond the cell" published in the Journal of Applied Physics.  Check it out here: https://doi.org/10.1063/5.0218262

The art shown above, by lab artist-in-residence, Vivian Wattle, will be featured on the journal cover!

Group attends APS March Meeting

3/3- 3/8/2024

The Kisley Lab took over the APS March Meeting in Minneapolis! The group had seven talks & one poster over the course of the meeting in DBIO, DSOFT, DCP, DPOLY, DFD, and GIMS.

Contact Us

Rockefeller Bldg.
2076 Adelbert Rd.
Cleveland, OH 44106-7079

216-368-2118

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